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Design Proteins with RFD4-Proteina Using Reward-Guided Inference-Time Search
Our short summary of NVIDIA’s engineering write-up. The full story, with all the detail, is on their blog.
Read the full write-up on developer.nvidia.com (opens in a new tab)Problem
Scientists need to explore billions of protein sequences to find therapeutic candidates, but exhaustive search is impossible.
Solution
They created a model that generates protein sequences and structures together, then runs a reward‑guided search at inference time, keeping and expanding promising partial designs until the goal is met.
Faster and uses less memory than the previous version
Want the architecture, code and numbers? They’re in the original post.
Read the full write-up on developer.nvidia.com (opens in a new tab)
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